25. Cong Sun, Fan Hong. De novo design of RNA switches for conditional transcription repression. Angewandte Chemie International Edition, 2026, In press
|
24. Yanju Chen, Ryan N. Delgado, Ethan Xu, Constance L. Cepko, Fan Hong*. Scaling up sequential stepwise DNA displacement-based signal exchange for rapid ultra-plex fluorescent imaging in cells and tissues. J. Am. Chem. Soc., 2026, 148, 44438–4449
Preprint: bioRixv
Preprint: bioRixv
|
23. Zhaoqing Yan, Yudan Li, Amit Eshed, Kaiyue Wu, Zachary M. Ticktin, Vel Murugan, Efrem S. Lim, Fan Hong*, Alexander Green*. Programmable Fluorescent Aptamer-Based RNA Switches for Rapid Identification of Point Mutations. Nature Chemistry, 2025,17, 1826–1838
Preprint: MedRxiv
See News&Views: Ultraspecific RNA switches for robust mutation detection, Nature Chemistry, 2025
Editorial Highlight: Sensing RNA, Nature Chemistry
Media outlets: ScienMag, Bioengineer.org, UF News
Preprint: MedRxiv
See News&Views: Ultraspecific RNA switches for robust mutation detection, Nature Chemistry, 2025
Editorial Highlight: Sensing RNA, Nature Chemistry
Media outlets: ScienMag, Bioengineer.org, UF News
|
22. Fan Hong*, Programmable DNA Reactions for Advanced Fluorescence Microscopy in Bioimaging, Small Methods, 2025, 9, 2401279
|
21. Fan Hong, Jocelyn Y. Kishi, Ryan N. Delgado, Jiyoun Jeong, Sinem K. Saka, Hanquan Su, Constance L. Cepko, Peng Yin*. Thermal-plex: Fluidic-free, rapid sequential multiplexed imaging with DNA encoded thermal channels. Nature Methods, 2024, 21, 331–341
|
|
20. Lan Liu, Fan Hong, Hao Liu, Xu Zhou, Shuoxing Jiang, Petr Sulc, Jianhui Jiang*, Hao Yan*. A localized DNA finite-state machine with temporal resolution. Science advances 8.12 (2022): eabm9530.
19. Aidan Tinafar, Yu Zhou, Fan Hong, Kirstie L. Swingle, Anli A. Tang, Alexander A. Green, Keith Pardee. Cell-Free Biosensors: Synthetic Biology Without Borders, Handbook of cell biosensors, Springer, 2022
18. Longlong Si,Haiqing Bai, Crystal Yuri Oh, Tian Zhang, Amanda Jiang, Fan Hong, Yongxin Ye, Tristan X Jordan, James Logue, Marisa McGrath, Chaitra Belgur, Atiq Nurani, Wuji Cao, Rani K Powers, Rachelle Prantil-Baun, Steven P Gygi, Matthew Frieman, Benjamin R tenOever, Donald Elliot Ingber. Self-assembling short immunostimulatory duplex RNAs with broad spectrum antiviral activity Molecular Therapy-Nucleic Acids, 2022, 29: 923-940.
17. Hao Liu, Fan Hong, Francesca Smith, John Geortz, Thomas Ouldrige, Molly M. Stevens, Hao Yan, Petr Sulc, Kinetics of RNA and RNA:DNA Hybrid Strand Displacement , ACS Synthetic Biology, 2021, 10(11): 3066-3073.
16. Shuoxing Jiang, Nibedita Pal, Fan Hong, Nour Eddine Fahmi, Huiyu Hu, Matthew Vrbanac, Hao Yan, Nils G. Walter, Yan Liu, Regulating DNA Self-Assembly Dynamics with Controlled Nucleation, ACS Nano, 2021, 15, 5384-5396
15. Fan Hong, John Shreck, Petr Sulc, Understanding DNA interactions in crowded environments with a coarse-grained model, Nucleic Acid Research, 2020, 48, 10726–10738
13. Fan Hong, Duo Ma, Kaiyue Wu, Lida A. Mina, Rebecca C. Luiten, Yan Liu, Hao Yan*, Alexander A. Green*. Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators, Cell, 2020, 180(5): 1018-1032 [Design code]
Featured as the cover article of the issue
Highlighted by Nature Methods: Pinpointing RNA mutations.
See media coverage: TechnologyNetworks, ScienceDaily, Phys.org, Science Codex, EurekAlert, GENnews, GenomeWeb, featured in Coriell Institute.
Highlighted by Nature Methods: Pinpointing RNA mutations.
See media coverage: TechnologyNetworks, ScienceDaily, Phys.org, Science Codex, EurekAlert, GENnews, GenomeWeb, featured in Coriell Institute.
|
|
12. Fan Hong, Petr Sulc. An emergent understanding of strand displacement in RNA biology, Journal of Structural Biology, 2019, 207(3): 241-249.
11. Fan Hong, Shuoxing Jiang, Xiang Lan, Raghu Pradeep Narayanan, Petr, Sulc, Fei Zhang, Yan Liu, Hao Yan, Layered-Crossover Tiles with Precisely Tunable Angles for 2D and 3D DNA Crystal Engineering, J. Am. Chem. Soc. 2018, 140, 14670-14676.
10. Shuoxing Jiang #, Fan Hong#, Huiyu Hu, Hao Yan, Yan Liu, Understanding the Elementary steps in DNA tile-based self-assembly. ACS nano, 2017, 11, 9, 9370-9381. #Contributed Equally.
9. Fan Hong, Fei Zhang, Yan Liu, Hao Yan, DNA origami: scaffolds for creating high order structures. Chemical Review, 2017, 117, 20, 12584-12640
8. F. Zhang, F. Hong, H. Yan*, DNA Origami Tiles: Nanoscale Mazes, Nat. Nanotechnol., 2017, 12, 189-190.
7. Fan Hong, Shuoxing Jiang, Tong Wang, Yan Liu, Hao Yan, 3D Framework DNA origami structure with layered crossover motifs. Angew Chem Int Ed, 2016,55,41, 12832-12835.
6. Xiaowen Ou, Fan Hong, Zhenyu Zhang, Yong Chen, Zujin Zhao, Pengcheng Gao, Xiaoding Lou, Fan Xia*, Shutao Wang, A highly sensitive and facile graphene oxide-based nucleic acid probe: Label-free detection of telomerase activity in cancer patient's urine using AIEgens, Biosensors and Bioelectronics, 2016, 89, 417-421.
5. Wei Guo #, Fan Hong#, Nannan Liu#, Jiayu Huang, Boya Wang, Ruixue Duan, Xiaoding Lou, Fan Xia*. Target-Specific 3D DNA Gatekeepers for Biomimetic Nanopores, Advanced Materials, 2015, 27(12): 2090-2095. # Co-first author, Contributed Equally.
4. Ruixue Duan, Boya Wang, Fan Hong, Tianchi Zhang, Yongmei Jia, Jiayu Huang, Abdul Hakeem, Nannan Liu, Xiaoding Lou, Fan Xia*, Real-time monitoring of enzyme-free strand displacement cascades by colorimetric assays. Nanoscale, 2015,7, 5719-5725.
3. Di Kang, Ruixue Duan, Yerpeng Tan, Fan Hong, Boya Wang, Zhifei Chen, Shaofang Xu, Xiaoding Lou, Wei Wei, Bernard Yurke, Fan Xia*, Speeding up the self-assembly of DNA nanodevice by variety of polar solvents. Nanoscale, 2014, 6, 14153-14157.
2. Abdul Hakeem, Ruixue Duan, Boya Wang, Fan Hong, et al, Dual Stimuli-Responsive Nano-Vehicle for Controlled Drug Delivery: Mesoporous Silica Nanoparticles End-Capped with Natural Chitosan, Chemical Communications, 2014,50, 13268-13271
1. Yongmei Jia, Ruixue Duan, Fan Hong, Fan Xia*. Electrochemical Biocomputing: A New Class of Molecular-Electronic Logic Devices. Soft Matter, 2013, 9, 6571-6577