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Fan Hong
Principal Investigator Email: [email protected] Office: CLB 210C Affiliations: Assistant Professor, Department of Chemistry, University of Florida Affiliated Professor, J. Crayton Pruitt Family Department of Biomedical Engineering Member of McKnight Brain Institute, UF Health Cancer Center, UF Genetics Institute Education/Training: Postdoc - Wyss Institute at Harvard University & Harvard Medical School Ph.D. - Biodesign Institute & Arizona State University B.S. - Huazhong University of Science and Technology |
Fan is interested in developing biomolecular tools to dive into the complexity of biology (decoding and regulating cellular function on the molecular basis in the single cell level at the tissue scale). Before joining the faculty at the University of Florida, Fan was a Postdoc Fellow at Wyss Institute at Harvard University where he worked on the DNA advanced in situ spatial multi-omics (e.g., DNA thermal-plex) in the Yin Lab. Thermal-plex enables multiplexed fluorescent imaging of biomolecules with unprecedented feasibility and speed for tissue biospecimen analysis. Fan completed his Ph.D. at Biodesign Institute at Arizona State University and worked in the Yan Lab, Green Lab, and Sulc Lab, where he developed methods to program nucleic acids in vitro (e.g., Framework DNA nanoarchitecture), in vivo (e.g., SNIPR), and in silico (e.g., crowder-oxDNA) to address grand questions with chemical approaches to biology. Those methods enable the control of nucleic acid folding into complex framework biomolecular architectures from the nanoscale to the macroscale, the regulation of cellular gene expression based on the single nucleotide mutation in cells with de-novo-designed RNA riboregulators, and the investigation of the biophysical behavior of nucleic acid folding in the crowding cellular environment with molecular dynamics.
We are actively recruiting Postdocs and graduate/undergraduate students, come to join us on the exiting journey!
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